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Cell-culture time courses Cell-culture studies in tendon-derived and fibroblast cell populations report observable changes in cellular migration, proliferation kinetics and gene-expression in growth-factor pathways over a window of hours to several days

Taking progress photos and maintaining brief daily notes helps identify changes that accumulate slowly

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Other molecules can be captured within ices, in the form of clathrate hydrates

doi:10.1016/j.ejrad.2021.109722

Analytical verification requires reverse-phase HPLC with UV detection at 214-220 nm to confirm retention time consistency and peak purity above 95%, while mass spectrometry (MALDI-TOF or ESI-MS) can confirm the expected molecular ion at 1419.53 Da and identify any truncation or oxidation products