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Vitamin B12 injections are generally safe, but some individuals may experience side effects, including: Pain or redness at the injection site Mild diarrhea Itching Nausea or vomiting Dizziness or headaches Hot flashes In rare cases, more serious reactions, such as allergic responses (rash, swelling, trouble breathing), can occur

However, a different trial by Wrone et al

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The appearance of an asthma attack in some patients may be related to allergy to aspirin or other NSAIDs