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Drug reimbursement is calculated separately

Characterization of the metabolic interactions between folate and methionine in the regulation of SAM-dependent homocysteine levels, as assessed by Selhub and Miller (Miller et al, 1994a, 1994b

However, it is not known whether vitamin B 12 supplementation, in addition to folic acid supplementation, may be beneficial in the prevention of NTD (62) randomized controlled trials are needed to address this question

doi: 10.3389/fnagi.2017.00089 99 LuanH.LiuL

This concept implies that the autoimmune response can be theoretically stopped and perhaps reversed if the interplay between autoimmune predisposing genes and trigger(s) is prevented or eliminated

Awad, K