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In cases of cellular injury, there is an observed increase in the production of reactive oxygen species (ROS)

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Oxidative stress has been associated with the onset and progression of mild cognitive impairment (MCI) and Alzheimer disease (AD)

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- Vitamin C is an external antioxidant that, together with glutathione and vitamin E, forms a non-enzymatic antioxidant system in cells

Therefore, cross-reactivity between different types of sulfonamides and sulfonamide-type antibiotics is not clearly demonstrated, and allergic reactions may involve other mechanisms