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Cholesterol efflux by high density lipoproteins is impaired in patients with active rheumatoid arthritis

For example, carriers that facilitate brain delivery of neurotrophic factors promote hippocampal neurogenesis in stressed animals [8, 29, 65]

Mol.Genet.Metab 2008;94(3):287-291

Moreover, FFAs increase high-density lipoprotein (HDL) clearance, leading to a decrease in HDL [53]

Device and platform compatibility matters

Using a targeted CRISPR knockout library consisting of 64 KGDDs, we discovered that trimethyllysine hydroxylase epsilon (TMLHE), the first and rate-limiting enzyme in de novo carnitine synthesis, is necessary for the survival of HR-proficient cells in the presence of DNA-damaging agents