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Moreover, it was reported that the activation of the AMPK signaling pathway played the critical role in the recovery from exercise in patients with type 2 diabetes (Kjbsted et al., 2016)
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Cell Chem Biol 23:12061216
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Long-term mildronate treatment increased Proteobacteria level in gut microbiome, and caused behavioral deviations and transcriptome change in liver, heart and brain of healthy mice
23 However, their use is limited by anticholinergic side effects, especially in elderly patients and those with cardiovascular disease
