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It incorporates the prediction of oral toxicities of chemicals which can be measured at different levels of toxicity mainly qualitatively in terms of endpoints as binary output (active or inactive) along with confidence scores such as acute toxicity, hepatotoxicity, carcinogenicity, immunotoxicity, mutagenicity, cytotoxicity, adverse outcome (Tox21) pathways, and toxicity (LD50) values in mg/kg body weight

[DOI] [PubMed] [Google Scholar] McHill AW, Smith BJ, Wright KP., Jr Effects of caffeine on skin and core temperatures, alertness, and recovery sleep during circadian misalignment

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Mitochondrial Resilience and Energy Homeostasis By stimulating AMPK and NRF2 pathways, MOTS-C peptide helps maintain mitochondrial function under stress

CMS requires modifier JW or JZ on applicable Part B drug claims

Stoddart et al