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Description
Accordingly, acute carnitine deficiency induced by excessive conversion of free carnitine to acetylcarnitine could lead to detrimental changes in mitochondrial functionality during ischemia and intensive exercise

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Carnitine palmitoyltransferase 1 (CPT 1) is an enzyme located on the outer mitochondrial membrane: it catalyzes the esterification of long chain acyl-coenzyme A to acyl-carnitine

Then, L-theanine alone or in combination with theobromine could effectively inhibit tumor production in male Wistar rats with colon cancer induced by dimethylhydrazine, and the mechanism of action was related to downregulating the Akt/mTOR (mammalian target of rapamycin) and JAK2/STAT3 pathways and increasing the mRNA and protein expression of tumor suppressor Smad2 (73)

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