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In COPD, repeated exposure to noxious particles, usually cigarette smoke, can activate epithelial cells and macrophages to release variety of chemotactic factors that attract inflammatory cells (eg, CD8 + T lymphocytes, neutrophils, monocytes) to the lungs, triggering a distinct inflammatory cascade in the small airways and lung parenchyma

In addition, peroxidase catalyses the oxidation and reduction of the substrate by using hydrogen peroxide (Fig

Gaillard, J.-M

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These data indicate that LT may exert a preventive effect on PCOS by modulating bile acid metabolism, providing a basis for the potential of LT in preventing PCOS