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Pulse-chase studies in coelomocytes have shown that CUP-5 is required for the biogenesis of lysosomes, the earliest MLIV-associated defect in the endocytic pathway that has yet been described [16]

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On April 26, 2020, clinicians in the U.K recognized increased reports of previously healthy children presenting with a severe inflammatory syndrome with Kawasaki disease-like features.[2] The Royal College of Paediatrics announced in a statement most kids are asymptomatic or exhibit mild symptoms when infected with COVID-19