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Hepatology 30:186195 Mitchell JR, Jollow DJ, Potter WZ, Gillette JR, Brodie BB (1973) Acetaminophen-induced hepatic necrosis
10.1093/geronj/11.3.298 68 HarmanD
SAG (30 mg/kg) was administered orally for 8 weeks
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The epigenome is, indeed, influenced by metabolic factors (intracellular flux or availability of metabolites, drugs, eating habits and metabolic fitness) and environmental parameters in the strict sense (presence of pollutants, social relationships, mental and relational stress) 10
Conversely, in the same model, aspirin administration has been shown to reduce stereotyped behaviors and anxiety-like responses [97]
