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The major importance of paracrine/autocrine IGF-I was demonstrated by liver specific Igf1 ko mice ( Ligf1 ko) with largely unaffected longitudinal growth (33)

Aldehyde dehydrogenase 1 family member L2 (encoded by the ALDH1L2 gene) was originally identified as mitochondrial 10-formyltetrahydrofolate dehydrogenase (mtFTD)

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Oxygenation of the newborn: a molecular approach

However, this effect appears to be tissue-specific, as Src activation enhances oxidative phosphorylation in brain mitochondria [10]

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