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We highlighted the role of ferroptosis in comorbidities and emphasized its relevance in cardio-cerebrovascular diseases associated with AS and psychiatric disorders, such as depression

Research into its anti-tumour potential in breast and colorectal cancer has been prompted by its alleged antioxidant activities and potential to decrease carcinogenic receptor expression

2015;5 doi: 10.1136/bmjopen-2015-008531

This remained true even when they were repeatedly put under very stressful situations

Indeed, LA is more frequent in patients with T1DM, presents mast cells and eosinophils at biopsy, and displays positive responses to mast-cell inhibiting treatment [6, 22]

It will be a major achievement to unravel those mechanisms and to steer these such that therapeutic targeting is most beneficial