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The more recent STEP UP trial tested a higher dose of 7.2 mg and showed average weight loss of 20.7% at 72 weeks

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The Fundamental Divide: Two Completely Different Mechanisms The three compounds split into two mechanistic families: Family 1 Growth-hormone fragment (direct lipolysis): AOD-9604 acts directly on adipose tissue, studied for stimulating lipolysis and inhibiting lipogenesis, independent of the IGF-1 receptor