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Early data is interesting, but rigorous science and patient safety must come first

It works by initiating inflammation, cleaning up tissue damage, and kickstarting the repair process

33,34,35,36,37 One study suggests that length of time from diagnosis of cognitive impairment is important for response rate, in that patients who had experienced symptoms for less than 12 months improved on B12, whilst those with symptoms for more than 12 months continued to decline

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Because NNMT activity intersects methyl donor utilization and nicotinamide handling, experimental inhibition can be used to probe pathway level relationships among methyl economy balance, NAD+ salvage flux, and downstream metabolic signaling in a range of preclinical systems

Worse, they either underdose and stall their progress or overdose and trigger side effects that could have been avoided entirely