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These results demonstrate that TSEL can improve cognitive deficits in APP/PS1 mice by acting synergistically with two genetic drugs to regulate the phenotype of activated microglia, reduce A accumulation, and prevent the re-triggering of neuroinflammation (Jiang et al., 2024)

Myths and Methodologies: Reducing Scientific Design Ambiguity in Studies Comparing Sexes and/or Menstrual Cycle Phases