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Alpha-Lipoic Acid and Male Pathologies: Clinical Studies Hodeeb and collaborators [103] evaluated the efficacy of ALA administration in primary infertile males with idiopathic asthenozoospermia

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Knockouts of the ThDP transporter SLC44A4 in mice display an upregulation of genes associated with colonic inflammation, and increased susceptibility to dextran sodium sulfate-induced colitis, accompanied by significant weight loss and shortening of the colon (204)