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doi: 10.1016/j.ymgmr.2021.100761
Oncotarget , 7 (36), 5840558417

Upon cuprizone treatment FAS mRNA expression level was up-regulated during the first 2 weeks in the CC and thus, correlates with the expression pattern of activated caspase-3 in oligodendrocytes

As noted by Kraus et al., Nature Medicine , NNMT inhibition in white adipose tissue significantly increased energy expenditure and reduced fat mass in animal models without changes to diet or activity
The selectivity is remarkable
