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Some chemotherapeutics cause coasting of symptoms, the progressive worsening of neuropathy after cessation of treatment, and in severe cases CIPN can develop into an irreversible sensory neuron deficit

(PubMed) Kristal AR, Darke AK, Morris JS, et al

2022;7(16): e160909

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[DOI] [PMC free article] [PubMed] 612.Yang P, Feng J, Peng Q, Liu X, Fan Z

To examine whether PlexinB1 affects the nuclear/cytoplasmic ratio of Ran, PlexinB1 expression was knocked down in HeLa, MCF and PC3 cells, and the expression levels of Ran in the nucleus and cytoplasm were recorded using immunofluorescence
