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HLCs derived from the growth factor protocol displayed mature hepatocyte morphological features including a raised, polygonal shape with well-defined refractile borders, granular cytoplasm with lipid droplets and/or vacuoles with multiple spherical nuclei or a large centrally located nucleus
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The study concluded that Merestinib has a tolerable safety profile and potential anticancer activity, warranting further clinical investigation [125]

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[DOI] [PubMed] [Google Scholar] 108.Visioli F., Riso P., Grande S., Galli C., Porrini M
