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However, it is known that the placental dysfunction is often gradual and it can occur much earlier than any demonstrable IUGR[188], thus difficulting the resolution of this hypothesis

doi:10.1002/jcb.22541 Spergel DJ

We also analyzed the expression of IL-6 and -8, which however were not detectable due to the low expression level

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There is no human clinical data establishing a timeline for gut-specific effects