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What remains a subject of ongoing debate is the extent to which triglycerides directly promote atherogenesis or, alternatively, simply represent a biomarker for other processes that influence cardiovascular risk

One broad definition of GST is,

chimeric constructs are provided that expand beyond targeted chemotherapy to immunotherapy by incorporating, for example, providing bispecific antibodies comprising an anti-ALPP/ALPPL2 antibody attached to a second antibody that is capable of recruiting and activating immune system components or attached to a moiety that is a checkpoint inhibitor e.g., anti- CTLA4 e.g., comprising an ipilimumab variable region), and/or antibodies directed against PD-L1 e.g., comprising an nivolumab, or pembrolizumab variable region), and/or antibodies directed against PD-L2

The Krebs cycle, which, due to oxidative stress, favors the increase of the number of proton donors in the mitochondria, the main source of free radicals [37, 40]

The balance between M1 and M2 macrophages is crucial for maintaining health, and dysregulation of this balance is implicated in various clinical conditions [12]