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Description
Mensah Medical

Thioesterase superfamily member 2/Acyl-CoA thioesterase 13 (Them2/Acot13) regulates adaptive thermogenesis in mice

Finally, the sample size was very small

Leading to Discontinuation of Treatment Approximately 20% of 3616 patients who received clomipramine in U.S

Borthakur G , Ofran Y, Tallman MS, Foran J, Uy GL, DiPersio JF, Showel MM, Shimoni A, Nagler A, Rowe JM, Altman JK, Abraham M, Peled A, Shaw S, Bohana-Kashtan O, Sorani E, Pereg Y, Foley-Comer A, Oberkovitz G, Lustig TM, Glicko-Kabir I, Aharon A, Vainstein-Haras A, Kadosh SE, Samara E, Al-Rawi AN, Pemmaraju N, Bueso-Ramos C, Cortes JE, Andreeff M

The extensive R-domain and NBD1 interactions increase the ATPase rate in a manner consistent with CFTR, where R-domain phosphorylation potentiates ATP binding and hydrolysis but otherwise does not induce transport activity alone 34
