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2017 study linked very high long-term B12 supplementation to lung cancer risk in male smokers, though the finding was not replicated in a 2019 Norwegian cohort study Cystic acne flares and rare cobalt-related allergic reactions are the most documented real-world adverse effects of high-dose B12 Test serum B12, MMA, and homocysteine before adjusting your dose

And without adequate protein to support muscle synthesis, more of the GH-mobilized energy may be wasted

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