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A singletunnel or doubletunnel technique can be used (D'Oria et al., 2022)

By creating uniform and transient microchannels in the stratum corneum, RF facilitates the deeper penetration of liposomes through otherwise impermeable skin barriers

doi: 10.1016/j.bbadis.2020.166037 194

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Endlicher R, Drahota Z, tefkov K, ervinkov Z, Kuera O
