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It is important to note that the majority of this mechanistic research has been conducted in cell culture and animal models, with a significant proportion originating from a single research group
However, molecular analysis reveals that 126 DNA methylation sites remain altered (112), while 23 genes exhibit sustained expression changes (113), suggesting residual heritable effects that may contribute to long-term reproductive vulnerabilities
Current Protein & Peptide Science, 17(3), 253-261
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