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( B ) Ppargc1a mRNA levels in AC16 cells treated with 50 M rosiglitazone (PPAR agonist), 50 M WY-14643 (PPAR agonist), a combination of rosiglitazone and WY-14643, or a combination of rosiglitazone, WY-14643, and 10 M MK886 (PPAR antagonist) ( B

This classification is generally mirrored by similar regulatory bodies worldwide (e.g., TGA in Australia, EMA in Europe)

This mechanism, if confirmed in human trials, would place GHK-Cu among a very small class of naturally occurring compounds with both anti-inflammatory and anti-androgen properties

This process occurs via a special set of enzymes, called Cytochrome P450

PREVIEW Wells Fargo & Company Q1 2022 Earnings Conference Call April 14, 2022 Executives in Attendance: John Campbell - Director, IR Charlie Scharf - CEO Mike Santomassimo - CFO Analysts Present: Scott Siefers - Piper Sandler Steven Chubak - Wolfe Research John Pancari - Evercore ISI Ken Usdin - Jefferies John McDonald - Autonomous Research Ebrahim Poonawala - Bank of America Betsy Graseck - Morgan Stanley Matt OConnor - Deutsche Bank Erika Najarian - UBS Charles Peabody - Portales Partner Gerard Cassidy - RBC Capital Market Erika Najarian - UBS Comments from Charlie Scharf - CEO: Now, let me update you on progress weve made on our strategic priorities