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1 Introduction Inflammatory bowel disease (IBD) is a group of diseases characterized by chronic inflammation of the gastrointestinal (GI) tract, with periods of exacerbation and remission

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Inhibition of LDHA decreases the inflammatory response induced by bTNF- in bFLS As previously demonstrated, bTNF- increases the expression of LDHA, an enzyme that converts pyruvate to lactate with the production of NAD +

This study demonstrated that wireless optogenetics can be used to stimulate the ENS and increase colonic transit in conscious, freely moving animals