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Even though the 3D structure of OCTN2 is still not known, the molecular determinants for substrate specificity have been revealed: one ammonium and one carboxylate groups are strictly required for transport, while the distance between them is not important (Pochini et al., 2013)

Nature 379:723725 Gendron CM, Kuo TH, Harvanek ZM, Chung BY, Yew JY, Dierick HA, Pletcher SD (2014) Drosophila life span and physiology are modulated by sexual perception and reward

If youre experiencing redness, hot sensations, or tenderness of the skin, its time to seek shade, cool off, and rehydrate