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Still, caution remains appropriate

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Most researchers start conservatively at 0.5-1mg per actuation and titrate based on observed effects

Patients with a history of eating disorders, seizures, uncontrolled hypertension, or current use of opioid medications should avoid Contrave due to contraindications and safety concerns

"I've seen all ends of the spectrum with GLP-1s, some good, some negative, James Burns, MS, RD, CSSD, a performance dietitian practicing in Raleigh, North Carolina, told me

But what some people dont understand is that when they stop taking the medication, they may gain all that weight back. (The current study did not evaluate weight gain after the discontinuation of GLP-1 medications.) GLP-1 medications act as a pharmaceutical version of a natural hormone in the gut, lowering blood sugar, keeping you feeling fuller longer and slowing down digestion