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Preoperative data comprised the distance of the tumor from the anal verge, hemoglobin level, albumin level, presence of bowel obstruction, neoadjuvant therapy (chemotherapy, targeted therapy, immunotherapy, and radiotherapy), and neoadjuvant radiotherapy status

doi: 10.1074/jbc.272.5.2700

B.JakowecM.PetzingerG.MillerR.et al