how does glutathione affect the brain Research Communities by Springer Nature Do glutathione and copper interact

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The antioxidant alpha-lipoic acid (LA) can regulate the expression of proteins involved in the p53/caspase- 3 pathway in UC mice, inhibiting intestinal cell apoptosis while also suppressing colonic oxidative stress and ferroptosis [33]

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Although prior work indicates that ferroptosis acts as a central hub linking reactive oxygen species to autophagy and apoptosis, this study does not establish its priority within the cascade of oxidative stress, neuroinflammation, and multimodal cell death, particularly regarding microglial ferroptosis and its contribution to secondary neuronal injury