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Many lower vertebrates including fish, frogs, and birds have both AGAT and GAMT activities in their livers and kidneys, which is in contrast to mammalian and avian species [28, 29]

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This indicates that GAD67 is not only involved in maintaining metabolic levels of cellular GABA but may also contribute to the rapid vesicular accumulation of GABA in the presynaptic terminal for covering the incremental needs of synaptic neurotransmission by vesicular release into the synaptic cleft (Kanaani et al., 2010)

Step-by-step mixing, dose chart 0.25mg2.4mg, 10mg & 20mg vials