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Heliyon 6, e03659.CrossRefGoogle ScholarPubMed Xiao, B, Zhang, Z, Viennois, E, Kang, Y, Zhang, M, Han, MK, et al

XJB-5-131 significantly inhibits the increase of tert-butyl hydroperoxide-induced ferroptosis-driving factors (PTGS2, TFR1, and ATF3) and the accumulation of ferroptosis markers (Fe 2+ , ROS, and lipid peroxide) in chondrocytes

The study found that those who were GAD65 positive and also had low fish intake had a significantly higher risk of diabetes, with more than a fourfold risk of diabetes among those with both high levels of GAD65 antibodies and low omega-3s compared to those who were negative for GAD65 and had high omega-3 levels

Pfeffer PE, Hawrylowicz CM

Alterations in the GM composition can lead to the disruption of the intestinal epithelial barrier, provoked by gut-derived compounds, which may permit microbes and microbiota-derived unhealthy metabolites to enter the circulation and be transported to the brain through the gut-brain axis [49, 50]

The druglike and orally bioavailable compounds identified herein are active in animal models of schistosomiasis with a broader range of developmental stages targeted than the drug of choice, PZQ