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Introduction With the improvement in living standards, most people are more inclined to have high-energy diets and sedentary lifestyles, which greatly increases the risk of inducing obesity

In contrast to the phosphorylation of ACC2 by AMPK during energy-deficient states, hydroxylation of ACC2 increases under conditions of high glucose content, in particular in skeletal muscle

Conformational rigidity: MT-II is conformationally constrained by the 23-membered lactam ring, which pre-organizes the pharmacophore (His-D-Phe-Arg-Trp) into a defined spatial arrangement

Enzymes as biocatalysts in the modification of natural lipids

Correctly folded E1E2 for each HCVpp was confirmed with a panel of well-characterized mAbs (Supplementary Table 1)

calcium Ascorbate