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Conclusions Although challenges associated with some of these compounds remain, important advances have been made in the development of safer and more effective drugs that could actually represent a breakthrough for fatal degenerative diseases such as ALS

The altered calcium metabolism was thought to contribute to the increased skeletal fragility noted in acromegalic patients [110]

2006;576(Pt 1):27988

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Knowing that gene expression changes are responsible for cellular differentiation, these researchers used changes in cellular phenotypes as a proxy for gene expression changes (Table 1