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The Protamine Family of Sperm Nuclear Proteins

Notably, while classical organoid systems have long been established exclusively from crypt-resident stem cells 27,28 , our findings challenge this longstanding paradigm by demonstrating that mutation-free villus-derived cells can indeed establish organoids via fetal reversion, revealing remarkable regenerative flexibility of the adult intestinal epithelium

doi: 10.1016/j.bbagen.2018.05.018 99 WuSHOldfieldJEWhangerPHWeswigPH

doi: 10.2337/db06-0035 147 Saif-AliRHarunRKamaruddinNAAl-JassabiSNgahWZ

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