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Blood-brain barrier breakdown in Alzheimer's disease: Mechanisms and targeted strategies

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Stress, poor diet, pollution, and unhealthy habits like smoking and drinking also reduce its levels

Caffeic acid is majorly found in vegetables and fruits, most commonly esterified with quinic acid as in chlorogenic acid, the main phenolic in coffee

The mass spectrometer is then able to detect all atoms of interest

They serve as biomarkers for both oxidative and carbonyl stress