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E.ButyugovA

A significant proportion of patients will relapse with drug-refractory disease, necessitating the development of novel therapeutic approaches

In addition to its role in regulating calcium and phosphate metabolism and maintaining skeletal structure, vitamin D also exhibits anti-inflammatory effects

During fasting, SIRT3 upregulates -oxidation and ATP generation [177], inhibits ROS, and enhances mitochondrial biosynthesis by peroxisome proliferators-activated receptor coactivator lalpha (PGC-1) activation [178]

Nature (2009) 457(7227):31821

"The origin of the genetic code and of the earliest oligopeptides"
