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While supplements arent solely designed to replace food nutrients, they also cannot replace the essential role of proper eating

however, clinical trials have not consistently supported these uses

Yeunkum Lee et al

According to IKDSG guidelines, KD use is strictly contraindicated in patients with a deficiency of carnitine (primary), carnitine palmitoyltransferase (CPT) 1 or 2, carnitine translocase, pyruvate carboxylase, medium-chain acyl-coenzyme A (CoA) dehydrogenase (MCAD), long-chain acyl-CoA dehydrogenase (LCAD), short-chain acyl-CoA dehydrogenase (SCAD), and disorders of fatty acid -oxidation and porphyria

The main AEs included abdominal pain, nausea, and other gastrointestinal reactions, vomiting, headache, and so on [64]

[1] [2] It represents a novel therapeutic class as the first dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist