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Aside from this single case report, a RCT on the effect of a broccoli sprouts extract administration in 45 patients for 84 days demonstrated no variations in TSH, FT4, anti-TPO and anti-Tg autoantibodies positivity rate [158]

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As MASLD and MASH is associated with an underlying inflammatory metabolic state, these markers reflect underlying disease pathways, including apoptosis, inflammation, oxidative stress, and abnormal signaling pathways are involved