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In the phylogenetic tree of GST sequences from multiple species constructed by Herv [32], the GSTs of red and brown algae had a closer evolutionary relationship with the sigma GSTs from animals

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10.1016/j.ecl.2020.02.009 [DOI] [PubMed] [Google Scholar] Holladay C., Abbah S

Furthermore, in vivo experiments showed that CNS exhibited therapeutic effects comparable to those of fluoxetine, effectively ameliorating symptoms of anxiety, despair, and anhedonia while also inhibiting microglial activation in the hippocampus of mice subjected to CUMS
