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Dietary changes, such as adopting low-glycemic index or Mediterranean-style diets, complement exercise by reducing systemic inflammation and insulin resistance (Scannell et al., 2022)

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In Schneider-Helmert's human studies (1985, European Archives of Psychiatry and Neurological Sciences), small cohorts of insomnia patients received DSIP via IV and showed some shifts in sleep stage architecture measured by polysomnography, but results were not consistent across all subjects and the studies lacked the statistical power of modern RCTs

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