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More precise and potentially higher levels of dopamine (Patriarchi et al., 2018) will likely be measured as more studies use newer electrochemical detection techniques that are enhanced with aptamers or molecularly imprinted polymers and enzyme-, aptamer-, and antibody-based biosensors, as well as more sensitive in vivo tools including fiber photometry and genetic dopamine sensors such as dLight (Patriarchi et al., 2018

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Estrous cycle and early-life stress are significant factors in visceral sensitivity, and fluctuations in EAAT function may be a factor that mediates central sensitization, likely through aberrant central circuitry involving both the ACC and the lumbosacral spinal cord

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Moreover, this combination has been revealed to be effective in reducing respiratory ailments associated with coronavirus disease 2019 (Miryan et al., 2021

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10.1002/mrm.22086 11

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The environment of Phe1035 can also be stabilised by nearby Arg446(Arg118) involved in the dmIR-ECD/hIR conserved hydrogen bonds triad with Tyr419(Tyr91) and Glu448(Glu120), with a potential Arg446 guanidinium--Phe1035(Phe705) interaction as well

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One health: a multifaceted concept combining diverse approaches to prevent and control antimicrobial resistance

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