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The water molecules themselves can participate in reactions (like hydrolysis) that break peptide bonds

If you still think B12 is just about haematology or even haematology and neurology then you are woefully under-educated

However, persistent or severe reactions should be evaluated by a healthcare professional

Vitamin B12 attenuates leukocyte inflammatory signature in COVID-19 via methyl-dependent changes in epigenetic markings

There are no known cases where the pH level alone caused tap water to be unsafe