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The cells' overall defense systems are essentially collapsing under the weight of the inflammation, leading to mitochondrial calcium overload and eventual energy failure

The peptides now categorized under Category 2 have not met these specified criteria

doi: 10.1016/j.bbamcr.2010.10.007

If this increase in GSH was blocked, liver regeneration was impaired (Huang et al., 2000a)

Moreover, high concentration of ROS produce mechanical stimulus, which causes stiffening of vascular wall (vasoconstriction) and leads to hypertension via accumulation of intracellular calcium concentration

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