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However, given that mRNA levels of myelin proteins are reduced at 1 week, when oligodendrocyte death is ongoing, the lower synthesis may be a consequence rather than a driver of oligodendrocyte toxicity (Fig

Recent research highlights IL-6s diverse biological effects, demonstrating its role in inducing the expression of various pro-inflammatory cytokines and chemokines, as well as regulating anti-apoptotic gene transcription and liver regeneration [144]

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