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Comparison of retention following intramuscular injection of cyanocobalamin and hydroxocobalamin
Rev Neurol (Paris) 172(1):313 Lokovic BV, Gottesman RF, Bernstein KE, Seshadri S, McKee A, Snyder H, Greenberg SM, Yaffe K, Schaffer CB, Yuan C, Hughes TM, Daemen MJ, Williamson JD, Gonzlez HM, Schneider J, Wellington CL, Katusic ZS, Stoeckel L, Koenig JI, Corriveau RA,, Chen J (2020) Vascular contributions to cognitive impairment and dementia (VCID): a report from the 2018 national heart, lung, and blood institute and national institute of neurological disorders and stroke workshop

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The results showed no significant differences in any of the indicators, indicating that FOXO4-DRI treatment did not adversely affect liver or kidney function or cell viability in mice (Supplementary Figures S2AC)
In peripheral tissue, senescent cells are cleared by macrophages
