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In metabolic syndrome, multiple factors due to oxidative stress cooperate to promote the progression of hypertension, including inflammatory adipokines, activation of the sympathetic nervous system, abnormal gut microbiota, and retention of water and sodium [131]

[DOI] [PMC free article] [PubMed] Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, Amin N, Schwikowski B, Ideker T

On paper, the combination addresses both sides of the energy balance equation through complementary mechanisms

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Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes coronavirus disease 2019 (COVID-19) and can be associated with serious complications, including acute respiratory distress syndrome