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10.1016/j.taap.2010.12.004 101 KhanM

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Other microbial metabolites such as lactate isomers, valerate, and branched-chain SCFAs are also present but at considerably lower concentrations [69, 70]

Dietary carnitine is abundant in red meat, poultry, and fish, with limited availability in plant-based foods

Understanding of type 1 diabetes mellitus: what we know and where we go

The age-related decline in mitochondrial biogenesis, impaired oxidative phosphorylation (OXPHOS), and increased reactive oxygen species (ROS) production create an energetic deficit, compromising ATP-intensive processes like protein synthesis and sarcomere maintenance ( Critically, the interplay between sarcopenia and obesity converges into a distinct clinical phenotype known as sarcopenic obesity, which represents a high-risk geriatric syndrome characterized by the co-existence of reduced muscle mass/function and excess adiposity ( Finally, ectopic fat deposition results from the inability of subcutaneous fat to expand healthily, leading to lipid spillover into muscle ( Figure 1 )